Genetic Predisposition
Individuals with a high genetic predisposition
Recognise program to identify and treat an individual early
Recognising first-degree relatives for mental health conditions
First-degree relatives have a significantly higher risk of mental illnesses like schizophrenia and bipolar disorder. Advances in genome profiling have identified key genetic markers, aiding in risk prediction.
Evidence Base
First-degree relatives are at a much higher risk than the general population, especially for conditions like schizophrenia, bipolar disorder, and ADHD (Public Mental Health, 2019). There are now 150 genome-wide significant matches for schizophrenia, 19 for bipolar disorder, and 44 for major depression (Sullivan et al., 2018). According to Sullivan & Geshwind, genetics and genome profiling are powerful tools for predicting risk (Sullivan & Geschwind, 2019).